Inclusion Criteria:

1. Age≥ 18, ≤ 60 years old;

2. Have a fixed sex partner and regular sex life;

3. No previous infectious diseases, chronic diseases, tumor history, and male sexual
function and fertility diseases;

4. Normal erectile function, IIEF-5 score> 21 points;

5. Have complete clinical information and contact information；

6. Understand and sign the informed consent form.

Exclusion Criteria:

1. Hypertension, diabetes, coronary heart disease, hyperlipidemia and other chronic
diseases；

2. Past history of endocrine diseases such as hypopituitarism, hypogonadism, abnormal
thyroid function, etc;

3. Past history of mumps virus infection;

4. Past history of bladder cancer, prostate cancer, brain spine injury, testicular
injury, pelvic fracture, urethral injury and history of surgical treatment;

5. Severe cardiovascular and cerebrovascular diseases, severe lung diseases, severe
hepatitis;

6. Past psychological or mental illness;

7. Contact information not available.