Official Title
EMPOWER - BAME vs COVID: A Multi-site Clinical Cohort Research Study to Identify Genetic Associations and Candidate Therapeutic Targets to Reduce COVID-19 Morbidity & Mortality Rates in BAME Populations
Brief Summary

The COVID-19 virus pandemic has massively affected us all. Moreover, there is a disproportionately high number of COVID-19 severe infections and deaths in British Black, Asian and minority ethnic (BAME) patients. This clinical study plans to discover new ways of protecting people from this virus by looking at our DNA and biology.

Detailed Description

The COVID-19 virus pandemic has massively affected us all. We now know there is a much larger
proportion of British Black, Asian and minority ethnic (BAME) patients suffering from
COVID-19 infections. This disproportionate level of infection and severity of disease has
raised concerns and worries. Other research from April 2020 showed that 71% of the nurses and
midwives and 94% of the doctors and dentists that died of COVID-19 infections were from a
BAME background despite this group representing 20% and 44% of the workforce respectively.
The survival picture is also grim for Black and Asian members of the public where we see
disproportionately high rates of deaths. Research estimates that our DNA and the environment
equally influence the risk for infection. This clinical study plans to better understand our
DNA. Some of the things we will be looking at is age, sex, ethnicity and any illnesses such
as diabetes or blood pressure. We will ask people for some spit and look at their medical
records. This may help us find some of the reasons why this virus has different effects on
people and how we might protect people from COVID-19.

Withdrawn
COVID-19, SARS-CoV 2 Infection
Health Disparities
Eligibility Criteria

Inclusion Criteria:

1. All competent adult and children above the age of 5 years

2. Subjects agree to:

1. Gift saliva (spit) samples

2. Provide Consent for access to medical and health records

Exclusion Criteria:

1. Patient is not registered with the NHS for care.

2. Adults lacking capacity

3. Children under the age of 6 years.

Eligibility Gender
All
Eligibility Age
Minimum: 6 Years ~ Maximum: N/A
Countries
United Kingdom
Locations

Future Genetics Limited
Birmingham, West Midlands, United Kingdom

Dr Mohammed Kamran, Principal Investigator
Future Genetics Limited

Future Genetics Limited
NCT Number
Keywords
ethnic minority, health disparity, epidemiology, biomarker discovery, public health, BAME, morbidity, mortality, COVID-19, SARS-CoV-2
MeSH Terms
COVID-19