Patients infected with SARS-CoV-2 can present with a wide range of manifestationsclinical conditions, ranging from no symptoms to serious or chronic illness. The currentgold standard test for the diagnosis of COVID-19 is based on a molecular test of reversetranscription polymerase chain reaction (RT-PCR), aimed at detecting the RNA of the virusin respiratory samples such as nasopharyngeal swabs or aspirates bronchial, other methodssuch as antigen tests and serological detection tests IgM and IgG in response to COVID-19viral infection, can be used for the purposes of screening in the general population.In this context of variety of existing tests, it is important to monitor the biologicalparameters related to COVID-19 pathology by tracking the accuracy, specificity andsensitivity of these tests in current clinical practice.This research is a collection of additional biological samples with minimal impact on theintake usual care of the patients concerned, for the monitoring of biological parameterscarried out in routine on several reagent kits used for screening for the SARS-CoV-2virus, in terms of sensitivity, specificity, positive and negative predictive values, forthe implementation of indicators quality monitoring of these kits.