Introduction: Long COVID is characterized by persistent symptoms that persist for weeksor months after the acute phase of infection, with a significant impact on thecardiovascular and autonomic systems. Objectives: This study aims to evaluate the effectsof a physiotherapeutic rehabilitation protocol on cardiovascular autonomic modulation andon inflammatory and cardiac biomarkers in patients with Long COVID. Methodology: This isa controlled clinical trial, carried out in a cardiorespiratory rehabilitation outpatientclinic, involving individuals with a clinical diagnosis of Long COVID undergoing aprotocol of 20 aerobic, anaerobic and respiratory rehabilitation sessions. Heart ratevariability (HRV) variables will be analyzed using linear and non-linear methods, inaddition to serum levels of CKMB, LDH, ferritin and C-reactive protein. Expected results:Rehabilitation is expected to provide an improvement in autonomic function and areduction in inflammatory and cardiac markers, contributing to the understanding of thepathophysiological mechanisms of Long COVID and helping to propose evidence-basedtherapeutic strategies.
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Other: physiothreapy protocol
Aerobic training (treadmill or exercise bike) for 15 minutes, anaerobic training at the
weight training station, performing exercises for the upper limbs (bench press and front
pull) and lower limbs (180º leg press and extension chair) with weight determined by the
1 Repetition Maximum (1RM) test, performing 3 sets of 12-15 repetitions (depending on the
session) and respiratory muscle training using POWERbreathe (30-40% of the MIP performed
in the manovacuometry test).
Inclusion Criteria:
- both sexes
- aged 20 and 59 years
- clinical evaluation and undergoing clinical follow-up of Post COVID-19.
- least one persistent COVID-19-related symptom.
Exclusion Criteria:
- incomplete data.
- presence of a pacemaker
- use of antihypertensive drugs that alter HRV
- persistent pulmonary alterations
- persistent desaturation
- anaemia or presence of reinfection.
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Luiz Magno Falcão, Research and coordinator
+5591982379488
fabiofalcao@uepa.br
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