With the decline of virulence after the mutation of the SARS-CoV-2 , based on thenational life and health and national development needs, the domestic SARS-CoV-2infection epidemic prevention policy has changed, and the number of people infected bythe SARS-CoV-2 has increased. Nutritional status is an indicator of human health andplays an important role in fighting disease. Malnutrition has been found to correlatewith prognosis in patients infected with the SARS-CoV-2 infection . Timely identificationand assessment of the patient's nutritional status and early implementation of relevantnutritional intervention are conducive to the recovery of the patient's condition.In clinical practice, it is necessary to improve nutrition as an aspect of thecomprehensive diagnosis and treatment of patients with SARS-CoV-2 infection, but there isstill a lack of relevant nutritional indicators or models to simply and accurately assessthe nutritional status of patients.The purpose of this study was to evaluate the effectsof PNI, NRI, GNRI, albumin level, vitamin D, chest muscle area and density on theclinical characteristics and prognosis of patients with SARS-CoV-2 infection, to find thenutritional predictors of severe disease in patients with SARS-CoV-2 infection, and toestablish a simpler and more accurate nutritional evaluation model. To provide evidencefor targeted nutritional interventions in patients with SARS-CoV-2 infection.