The goal of this clinical trial is to assess the efficacy and safety of M-Gardsupplementation for alleviating the symptoms of allergic rhinitis.
Not Provided
Dietary Supplement: M-Gard
One capsule containing 250mg of M-Gard Particulate EW is taken twice daily for 14 days.
Other Name: M-Gard Particulate EW
Other: Placebo
One capsule containing 250mg of MCC (Microcrystalline Cellulose) is taken twice daily for
14 days.
Inclusion Criteria:
- Adults aged 18-65 years.
- Generally healthy
- Individuals with a history of recurrent seasonal allergic rhinitis
- Positive RAST test for grass allergy
- BMI 18-35kg/m2
- Able to provide informed consent
- Agree not to change current diet and/or exercise routine during entire enrolment
period
- Agree to not participate in another clinical trial during the study period
Exclusion Criteria:
- Serious illness e.g., liver disease, kidney disease, heart disease, mood disorders,
neurological disorders such as multiple sclerosis.
- Unstable illness e.g., diabetes and thyroid gland dysfunction.
- Current malignancy (excluding Basal Cell Carcinoma) or chemotherapy or radiotherapy
treatment for malignancy within the previous 2 years.
- Individuals with symptomatic perennial allergic rhinitis, non-allergic rhinitis,
chronic respiratory conditions (e.g., asthma, chronic obstructive pulmonary
disease).
- Participants with cognitive damage.
- Acute illness experienced in the past 1 month.
- Active smokers and/or nicotine or drug abuse.
- Allergic to any of the ingredients in the active or placebo formula.
- Chronic past and/or current alcohol use (>21 alcoholic drinks per week)
- Attempting to conceive, pregnant or lactating women
- Use of medications that would affect the immune and/or the inflammatory response
e.g. immunotherapy, antihistamines (daily use), corticosteroids, mast cell
stabilizers, leukotriene modifiers, and decongestants.
- Currently taking Coumadin (Warfarin), Heparin, Dalteparin, Enoxaparin or other
anticoagulation therapy including low dose aspirin; tricyclic antidepressants;
Clonidine and other central acting alpha-2-agonists.
- Participants who are currently participating in any other clinical trial or who have
participated in any other clinical trial during the past 1 month.
- Any condition which in the opinion of the investigator makes the participant
unsuitable for inclusion.
RDC Clinical
Brisbane, Queensland, Australia
Investigator: Amanda Rao
Contact: +61 (07) 3102 4486
amanda@rdcglobal.com.au
Amanda Rao
+61 (0) 7 3102 4486
research@rdcglobal.com.au
Thomas Tompkins, Study Director
Lallemand Bio-Ingredients