This cross-sectional observational study aims to determine the prevalence of PersistentCOVID-19 in 282 individuals in Punta Arenas, Magallanes and Chilean Antarctic Region.Persistent COVID-19 is a complex array of symptoms that persist or emerge for more than 4weeks beyond SARS-CoV-2 infection. Recent studies suggest that up to 80% of survivors maydevelop chronic multi-organ dysfunction due to persistent inflammation and immunedysregulation, making it an ongoing public health concern worldwide.The study aims to (1) describe and establish the frequency of physical and psychologicalsigns and symptoms in adult patients who have tested positive for COVID-19, (2) identifyindividuals who meet the WHO case definition of Persistent COVID-19 in Chile, (3) explorerisk factors associated with persistent COVID-19 to guide intervention strategies, and(4) explore inflammatory and molecular biomarkers associated with persistent COVID-19.The research project utilizes a stratified random sampling with a mixed-methods embeddeddesign. In the first phase, individuals diagnosed with COVID-19 will be recruited andfollowed up to complete the study's sample universe. A sociodemographic survey, bloodsampling (including complete blood count, biochemical profile, immunoglobulin mutationalstatus analysis, and analysis of inflammatory biomarkers), and a battery of psychologicaltests will be administered. In the second phase, kinesiology studies and medicalconsultation and evaluation will be conducted to determine if individuals have PersistentCOVID-19 and to derive them to the healthcare network. In the final follow-up phase,participants diagnosed with Persistent COVID-19 will be invited to undergomusculoskeletal and respiratory assessments to complete the diagnosis of symptomsassociated with the pathology.
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Other: Persistent COVID-19
To determine the prevalence of persistent COVID-19 diagnosis in the current study, we
will identify adults between 18 and 100 years of age who have had at least one positive
SARS-CoV-2 RT-qPCR test from the COVID-19 database maintained by the SEREMI of Health in
Punta Arenas between July 2022 and July 2023.
Inclusion Criteria:
- Age ≥ 18 years
- Individuals must be included in the COVID-19 monitoring database by the SEREMI of
Health in Punta Arenas between July 2022 and July 2023.
- Patients able to give informed consent.
Exclusion Criteria:
- Age < 18 years
- Any physical, mental, immunosuppressive, or social condition that, in the
investigator's judgment, might interfere with the completion of the baseline
assessments and evaluations.
- Individuals who are digitally illiterate and do not have access to nearby networks
to support them during the process.
Teaching and Research Healthcare Center of the University of Magallanes (CADI-UMAG)
Punta Arenas, Magllanes And Chilean Antartic Region, Chile
Investigator: Leyla Huirimilla Casanova
Contact: +56934206933.
fic.longcovid@gmail.com
Leyla Huirimilla Casanova, psychologist
+569 34206933.
fic.longcovid@gmail.com
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