We will include citizens referred for outpatient testing for COVID-19 who will be offered
to participante in the study on a volunteer basis. Participants are all volunteers, who
are attending the test facilities to obtain a PCR test. Participants are required to
provide oral and written informed consent to participate before entering the study. The
inclusion criterion is 18 years or more of age. Exclusion criteria are neck breathers
(tracheostomy/laryngectomy patients).

The participants will be randomized to either an oropharyngeal swap including the
palatine tonsils OR an oropharyngeal swap without the palatine tonsils for SARS-CoV-2
testing.

The swabs will be sent to the clinical microbiology laboratory for SARS-CoV-2 detection
using RT-PCR as usual. The diagnostic accuracy and SARS-CoV-2 viral load will be compared
using independent t-test. The participants will be asked to complete a questionnaire
regarding their symptoms and the number of sick days. All data will be documented on-site
in a secure web database (REDCap).

The primary outcome will be reported as:

• SARS-CoV-2 RNA by RT-PCR test result (positive, negative, inconclusive)

The secondary outcome will be reported as:

- SARS-CoV-2 RT-PCR cycle threshold (Ct) value

- Test discomfort on a 11-point NRS-scale

- Development of COVID-19 disease after testing

- SARS-CoV-2 detection rate for each healthcare worker

- Mallampati Score of participants being tested