Official Title
An Open Label Safety Study to Evaluate the Safety of Tipranavir Plus Ritonavir When Used in Combination With Other Agents for the Treatment of Patients With HIV Infection Who Have Failed and/or Are Intolerant to Combination Antiretroviral Therapy and Have Limited Treatment Options
Brief Summary

To provide early access to tipranavir and evaluate the safety and tolerance of tipranavircombined with low dose of ritonavir in patients with progressive, HIV-1 disease who havefailed or are intolerant to currently approved treatments for HIV infection, who areunable to participate in another tipranavir controlled clinical trial and have an urgentneed for anti-HIV treatment.

Approved for marketing
HIV Infections

Drug: Tipranavir

Tipranavir 250 mg soft elastic capsules

Eligibility Criteria

Inclusion criteria:

Patients aho have a positive serology HIV antibody test confirmed by Western blot, p24
antigen assay, HIV-1 RNA or HIV culture and are highly pre-treated and virus resistant to
multiple protease inhibitors.

Eligibility Gender
All
Eligibility Age
Minimum: 2 Years ~ Maximum: N/A
Countries
Australia
Belgium
Denmark
France
Greece
Ireland
Italy
Portugal
South Africa
Switzerland
United Kingdom
United States
Locations

1182.58.31
Scottsdale, Arizona, United States

1182.58.29
Los Angeles, California, United States

1182.58.34 Campus Code 696446
Los Angeles, California, United States

1182.58.42 Synergy Hematology/Oncology
Los Angeles, California, United States

1182.58.43
Los Angeles, California, United States

1182.58.03
San Francisco, California, United States

1182.58.33 Kaiser Permanente Medical Center, Clinical Trials Unit
San Francisco, California, United States

1182.58.37 AIDS Health Care Foundation
Los Angeles, Connecticut, United States

1182.58.41 Circle Medical, LLC
Norwalk, Connecticut, United States

1182.58.28
Washington, District of Columbia, United States

1182.58.38
Miami Beach, Florida, United States

1182.58.40 Drs. Raben and Feldman Research Associates
South Miami, Florida, United States

1182.58.23 Hillsborough County Health Department
Tampa, Florida, United States

1182.58.36 Suite 525
Atlanta, Georgia, United States

1182.58.08
Honolulu, Hawaii, United States

1182.58.22
Chicago, Illinois, United States

1182.58.32
New Orleans, Louisiana, United States

1182.58.15
Boston, Massachusetts, United States

1182.58.19 Henry Ford Hospital
Detroit, Michigan, United States

1182.58.04 Kansas City Free Health Clinic
Kansas City, Missouri, United States

1182.58.25 Wohl Clinic
St. Louis, Missouri, United States

1182.58.02 Wellness Center
Las Vegas, Nevada, United States

1182.58.09 Polari Medical Group
New York, New York, United States

1182.58.30
Chapel Hill, North Carolina, United States

1182.58.06 University of Cincinnati Medical Center, Infectious diseases
Cincinnati, Ohio, United States

1182.58.35
Portland, Oregon, United States

1182.58.14
Philadelphia, Pennsylvania, United States

1182.58.20 University of Pittsburgh
Pittsburgh, Pennsylvania, United States

1182.58.01 Boehringer Ingelheim Investigational Site
Columbia, South Carolina, United States

1182.58.10 Comprehensive Care Center
Nashville, Tennessee, United States

1182.58.18 University of Texas Southwest Medical Center at Dallas
Dallas, Texas, United States

1182.58.07
Houston, Texas, United States

1182.58.039 Olmos Park Medical Associates
San Antonio, Texas, United States

1182.58.11 Swedish Medical Center
Seattle, Washington, United States

1182.58.44 VW Hospital and Clinics
Madison, Wisconsin, United States

1182.58.61005 Royal Prince Alfred Hospital
Camperdown, New South Wales, Australia

1182.58.61008 St Vincents Hospital
Darlinghurst, New South Wales, Australia

1182.58.61011 St Vincents Hospital
Darlinghurst, New South Wales, Australia

1182.58.61014 St Vincents Hospital
Darlinghurst, New South Wales, Australia

1182.58.61007 407 Doctors Pty Ltd
Darlinghusrst, New South Wales, Australia

1182.58.61019 407 Bouke Street
Darlinghusrst, New South Wales, Australia

1182.58.61022 Sexual Health Clinic
Kingswood, New South Wales, Australia

1182.58.61012 Bigge Park Centre
Liverpool, New South Wales, Australia

1182.58.61003 The Prince of Wales Hospital
Randwick, New South Wales, Australia

1182.58.61002 Royal North Shore Hospital
St Leonards, New South Wales, Australia

1182.58.61006 Albion Street Clinic
Surry Hills, New South Wales, Australia

1182.58.61025 Immunology Department
Westmead, New South Wales, Australia

1182.58.61010 Biala Building
Brisbane, Queensland, Australia

1182.58.61009 Level 6
Herston, Queensland, Australia

1182.58.61024
Nambour, Queensland, Australia

1182.58.61016 Princess Alexandra Hospital
Woolloongabba, Queensland, Australia

1182.58.61020
Adelaide, South Australia, Australia

1182.58.61015 Flinders Medical Centre
Bedford Park, South Australia, Australia

1182.58.61001 88 Rathdowne Street Carlton
Carlton, Victoria, Australia

1182.58.61018 Melbourne Sexual Health Clinic
Carlton, Victoria, Australia

1182.58.61017 Department of Infectious Diseases
Clayton, Victoria, Australia

1182.58.61013 Melbourne Sexual Health Clinic
Melbourne, Victoria, Australia

1182.58.61023
Melbourne, Victoria, Australia

1182.58.61021
South Yarra, Victoria, Australia

1182.58.61004 Royal Perth Hospital
Perth, Western Australia, Australia

1182.58.3201 Boehringer Ingelheim Investigational Site
Antwerpen, Belgium

1182.58.3202 Boehringer Ingelheim Investigational Site
Bruxelles, Belgium

1182.58.3203 Boehringer Ingelheim Investigational Site
Bruxelles, Belgium

1182.58.3204 Boehringer Ingelheim Investigational Site
Liège, Belgium

1182.58.4505 Aarhus Universitetshospital Skejby
Aarhus C, Denmark

1182.58.4501 Rigshospitalet
København Ø, Denmark

1182.58.4504 Odense Universitetshospital
Odense C, Denmark

1182.58.33029 Hôpital Aix
Aix en Provence cedex 1, France

1182.58.33001 Hôpital Saint Jacques
Besançon cedex, France

1182.58.33022 Hôpital Avicenne
Bobigny cedex, France

1182.58.33020 Hôpital Antoine Beclère
Clamart cedex, France

1182.58.33028 Hôpital Louis Mourier
Colombes, France

1182.58.33027 Hôpital
Dijon cedex, France

1182.58.33034 Hôpital Raymond Poincarré
Garches, France

1182.58.33006 Hôpital Bicêtre
Le Kremlin Bicêtre cedex, France

1182.58.33019 Hôpital de l'Hôtel Dieu
Lyon cedex 2, France

1182.58.33031 Hôpital edouard Herriot
Lyon cedex 3, France

1182.58.33009 Hôpital de la Conception
Marseille cedex 5, France

1182.58.33023 Hôpital Sainte Marguerite
Marseille cedex 9, France

1182.58.33030 Hôpital Saint Eloi
Montpellier, France

1182.58.33032 Hôpital Emile Muller
Mulhouse cedex 1, France

1182.58.33008 Hôpital Hôtel Dieu
Nantes cedex 1, France

1182.58.33003 Hôpital de l'Archet
Nice cedex 3, France

1182.58.33013 Hôpital Saint Louis
Paris cedex 10, France

1182.58.33014 Hôpital Cochin
Paris cedex 14, France

1182.58.33007 Hôpital Georges Pompidou
Paris cedex 15, France

1182.58.33005 Hôpital Bichat
Paris cedex 18, France

1182.58.33017 Hôpital Bichat Claude Bernard
Paris cedex 18, France

1182.58.33033 Hôpital Tenon
Paris cedex 20, France

1182.58.33018 Hôpital Saint Antoine
Paris, France

1182.58.33024 Hôpital Necker
Paris, France

1182.58.33035 Hôpital des Abîmes
Pointe A Pitre, France

1182.58.33012 Hôpital Robert Debré
Reims cedex, France

1182.58.33026 Hôpital Ponchaillou
Rennes cedex 9, France

1182.58.33015 Hôpital Civil
Strasbourg cedex, France

1182.58.33025 Hôpital Foch
Suresnes cedex, France

1182.58.33021 Hôpital Chalucet
Toulon cedex, France

1182.58.33002 Hôpital Purpan
Toulouse cedex 9, France

1182.58.33016
Tourcoing, France

1182.58.33010 Hôpital Brabois
Vandoeuvre Les Nancy, France

1182.58.33011 Hôpital Paul Brousse
Villejuif cedex, France

1182.58.3001
Athens, Greece

1182.58.44029 Our Lady For Sick Children
Dublin 12, Ireland

1182.58.44016 St James Hospital, Dept of Genito Urinary Medicine
Dublin, Ireland

1182.58.3903 Università di Brescia
Brescia, Italy

1182.58.3904 Ospedali Riuniti di Foggia
Foggia, Italy

1182.58.3901 Ospedale Luigi Sacco
Milano, Italy

1182.58.3902 Ospedale L. Sacco
Milano, Italy

1182.58.3907 Presidio Ospedaliero di Rimini
Rimini, Italy

1182.58.3905 Presidio Dalmati
S. Angelo Lodigiano (lo), Italy

1182.58.3906 Ospedale Infantile Regina Margherita
Torino, Italy

1182.58.3908 Centro Medicina Preventiva
Verona, Italy

1182.58.35102 Hospital Condes Castro Guimarães
Cascais, Portugal

1182.58.27095 Boehringer Ingelheim Investigational Site
Cape Town, South Africa

1182.58.27098 Boehringer Ingelheim Investigational Site
Cape Town, South Africa

1182.58.27099 Boehringer Ingelheim Investigational Site
Cape Town, South Africa

1182.58.27096 Boehringer Ingelheim Investigational Site
Durban, South Africa

1182.58.27097 Boehringer Ingelheim Investigational Site
Westville, Durban, South Africa

1182.58.4101 Boehringer Ingelheim Investigational Site
Basel, Switzerland

1182.58.4103 Boehringer Ingelheim Investigational Site
Bern, Switzerland

1182.58.4104 Boehringer Ingelheim Investigational Site
Genève, Switzerland

1182.58.4107 Boehringer Ingelheim Investigational Site
Genève, Switzerland

1182.58.4102 Boehringer Ingelheim Investigational Site
Zürich, Switzerland

1182.58.4105 Boehringer Ingelheim Investigational Site
Zürich, Switzerland

1182.58.44020 Beckenham Hospital
Beckenham, United Kingdom

1182.58.44004 Boehringer Ingelheim Investigational Site
Brighton, United Kingdom

1182.58.44002 Boehringer Ingelheim Investigational Site
Cardiff, United Kingdom

1182.58.44025 Boehringer Ingelheim Investigational Site
Chertsey, United Kingdom

1182.58.44019 Boehringer Ingelheim Investigational Site
Chichester, United Kingdom

1182.58.44009 Boehringer Ingelheim Investigational Site
Edinburgh, United Kingdom

1182.58.44023 Boehringer Ingelheim Investigational Site
Harrow, United Kingdom

1182.58.44024 Boehringer Ingelheim Investigational Site
Leeds, United Kingdom

1182.58.44003 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44005 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44008 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44010 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44014 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44017 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44018 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44026 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44027 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44028 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44031 Boehringer Ingelheim Investigational Site
London, United Kingdom

1182.58.44011 Boehringer Ingelheim Investigational Site
Peterborough, United Kingdom

1182.58.44022 Boehringer Ingelheim Investigational Site
Woolwich, United Kingdom

1182.58.44030 Boehringer Ingelheim Investigational Site
Woolwich, United Kingdom

Boehringer Ingelheim, Study Chair
Boehringer Ingelheim

Boehringer Ingelheim
NCT Number
MeSH Terms
Infections
Communicable Diseases
HIV Infections
Acquired Immunodeficiency Syndrome
Tipranavir