Across every facet of life, 2020 tested our resolve and resilience. COVID-19 stretched our systems to the breaking point, exposing inexcusable gaps and limitations in our systems. As a force of creative destruction and reinvention, however, it also prompted new conversations, broke through barriers and accelerated the pace of innovation. This has been as much the case in the realm of real-world data (RWD) as it has anywhere.