During RAISE workshop V, Susan Winckler, CEO of the Reagan-Udall Foundation, and RDML Richardae Araojo, FDA Associate Commissioner for Minority Health and Director of the Office of Minority Health and Health Equity, welcomed everyone. During the session we heard three presentations. First, Dr. Carla Rodriguez-Watson, RAISE PI, summarized our previous RAISE workshops and their connection to workshop V. Then, Ronnie Tepp of Pyxis Partners presented a case study in community engagement and inclusion specifically focused on people of Middle Eastern or North African (MENA) descent. Finally, Dr. Susan Jenkins from the US Department of Health and Human Services discussed Statistical Policy Directive (SPD) 15, and the proposals to change SPD 15. The session closed with a discussion moderated by Sarah Greene, Senior Advisor to the National Academy of Medicine.