Recently published studies could demonstrate that detection of specific biomarkers in breath could be applied for the diagnosis of SARS-CoV-2.
In this study we want to address the sensitivity and specificity of breath analysis by
MCC-IMS in the context of SARS-CoV-2 detection from PCR- proven infected and non-infected
subjects.
Therefore nasal breath will be aspirated for 10 seconds during normal respiration by a foam
cuffed oxygen catheter connected via a 0.22μm filter and a line into the MCC-IMS and directly
analyzed without any pre-analytic procedures.
The during the proof-of-concept study derived significant peaks for volatile organic
compounds will be used for discrimination in a point-of-care approach.
Diagnostic Test: Multicapillary column coupled ion mobility spectrometry
sampling of nasal air via a foam cuffed oxygen catheter
Inclusion Criteria:
hospital admission staff members
Exclusion Criteria:
too sick to comply with study procedures
Klinikum Bayreuth/ Bayreuth General Hospital
Bayreuth, Germany
Investigator: Thomas Bollinger, MD
Contact: +49921400755810
thomas.bollinger@klinikum-bayreuth.de
Investigator: