Official Title
The Effects of Two Systems Above Low-flow Nasal Cannula on Arterial Oxygen Tension in Patients With COVID-19 : Surgical Face Mask Versus Double-trunk Mask
Brief Summary

This study will compare the impact of two systems above low-flow nasal cannula on the arterial oxygen tension in patients with COVID-19. The two systems are the Surgical Mask (SM) and the Double-Trunk Mask (DTM).

Detailed Description

Hospitalized patients with COVID-19 typically present with hypoxemia. In some patients,
hypoxemia can be corrected with low flow nasal cannula. When placed above nasal cannula, some
systems have demonstrated their interest in improving the performance of patient's oxygen
delivery. For example, two recent studies have shown that adding a Double-Trunk Mask (DTM) or
Surgical Mask (SM) above nasal cannula has the potential to improve the PaO2 despite no
change in oxygen output (Duprez et al., J Clin Monit Comput 2020; Montiel et al., Ann
Intensive Care 2020). However, there is no study comparing the relative effectiveness of
these 2 systems.

Completed
COVID19
Hypoxemia

Other: Standard Oxygen Delivery System

The standard oxygen delivery system (low-flow nasal cannula or oxygen mask) is worn by the patient for 1 hour.

Other: Double-Trunk Mask

The Double-Trunk Mask above the standard oxygen delivery system (low-flow nasal cannula or oxygen mask) is worn by the patient for 1 hour.

Other: Surgical Mask

The Surgical Mask above the standard oxygen delivery system (low-flow nasal cannula or oxygen mask) is worn by the patient for 1 hour.

Eligibility Criteria

Inclusion Criteria:

- COVID-19 positive

- SpO2 between 92 and 96% with low-flow oxygen therapy

- Oxygen output at baseline between 3 and 7 L/min.

Exclusion Criteria:

- Pulmonary disease with hypercapnia

- Confusion

- Contra-indications to arterial blood gas sampling (peripheral arteriopathy, bleeding
disorder)

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Belgium
Locations

Cliniques universitaires Saint-Luc
Brussels, Belgium

Cliniques universitaires Saint-Luc- Université Catholique de Louvain
NCT Number
Keywords
Double-Trunk Mask
surgical mask
MeSH Terms
COVID-19
Hypoxia