To develop an International registry on head and neck cancer patients infected withCOVID-19

A Phase I, double- blinded, randomized, placebo- controlled study to test the safety ofLomecel-B in Adults suffering from mild to severe acute respiratory distress syndrome(ARDS) due to COVID-19 resultant from 2019-nCoV coronavirus infection, or resultant frominfluenza virus infection.

This is study is comprised of three approaches. First, the investigators will conduct aretrospective cohort study to determine factors associated with COVID-19 severity andcomplications and understand COVID-19 outcomes, including all-cause mortality,post-discharge events, and impacts of rehabilitation services (third aim). The second aimis a mixed-method study and follows COVID-19 patients with repeated surveys to determinepatient-reported functional outcomes, health recovery, and rehabilitation needs afterCOVID-19. The investigators will recruit patients and their informal caregivers forinterviews to assess their function and rehabilitation needs.

To compare myocardial injury in COVID 19 patients presented with myocardial infarctionand non COVID Patients presented with myocardial infarction evaluated with CMR

On 30 January 2020, WHO declared the SARS-CoV-2 outbreak as a public health emergency ofinternational concern. Compared to SARS-CoV, which caused an outbreak of SARS in 2003,SARS-CoV-2 has a higher transmission capacity. Although the clinical manifestations ofSARS-CoV-2 are dominated by respiratory symptoms, some patients have severecardiovascular damage. In addition, patients with underlying cardiovascular disease maybe at increased risk of death. Therefore, understanding the impairments caused bySARS-CoV-2 to the cardiovascular system and the underlying mechanisms is of the utmostimportance.Circulating endothelial cells (CECs) are generally considered markers of lesions and maybe non-invasive markers of pulmonary vascular dysfunction during SARS-CoV-2 infection.Another marker of endothelial activation could be circulating extracellular vesicles.They could also be involved in the spread of the virus. Thus this project proposes tostudy different aspects of the diagnosis and pathophysiology of SARS-CoV-2. We propose tofully study activation state of coagulation and endothelium on a plasma and cellular sidein patients diagnosed with SARS-CoV-2/COVID19. The different forms of the disease will beincluded: without lung disease, with a more or less severe lung disease, i.e. havingevolved or not towards acute respiratory distress syndrome (ARDS). Extensive research ofbiomarkers will be compared to the detection of the virus in the respiratory tract aswell as in the blood. This work will contribute to a better description of diseasepathophysiology and should allow us to identify a patient profile in whom preventive orcurative anticoagulant therapy could be considered.

This study is to establish an accurate, robust and easily scalable COVID-19 viral nucleicacid analysis platform from, but not limited to, saliva to help enable and supportcontact tracing in the canton of Baselland/ Switzerland. To achieve this, cruderibonucleotide acid (RNA) extraction from saliva is validated in combination withnext-generation sequencing (NGS) diagnostics and loop mediated amplification (LAMP)assays as well as point of care test (POCT) for rapid detection of viral antigens onpatients' samples.

It is expected that large numbers of healthcare workers will experience a broad range ofpsychological reactions and symptoms including anxiety, depression, moral distress, andtrauma symptoms that will cause both significant suffering as well as occupational andsocial impairment. The purpose of this study is to find interventions which are helpfulin treating psychological distress in healthcare workers caring for COVID-19 patients.There are two phases of the study. All participants will take part in Phase I, whichconsists of 4 sessions over a two-week period of either a narrative writing interventionor a medical music intervention. Participants will be randomly assigned to the narrativewriting intervention or medical music intervention.After Phase I, participants will be re-assessed. Healthcare workers who meet criteria forPTSD will be given the option to participate in Phase II of the study, in which they willbe offered a choice between one of two evidence-based treatments for PTSD: InterpersonalTherapy (IPT) or Exposure Therapy (ET). Both treatments are comprised of ten 75-minutesessions scheduled twice weekly. Participants will be allowed to choose a preferredtreatment in Phase II. After Phase II participants will complete a final assessmentconcluding the study. All interventions will be offered using distance technology.

Study objective is to evaluate the efficacy of the combination of masitinib andisoquercetin in adult hospitalized patients with moderate and severe COVID-19.

Although recognized as an autoimmune disease the etiology of type 1 diabetes remainsunknown. Virus infections has been suggested as a possible agent triggering theautoimmune reaction finally resulting in beta-cell destruction and fate of insulinsecretion. SARS Cov-2 virus enters the infected cells by binding to the ACE-2 receptor,which is abundant in many tissues including the pancreas. Accordingly, SARS Covid-19infection may trigger the development of type 1 diabetes either by an activation of theimmune system or directly via beta-cell infection and destruction.Our aim is to study the impact of the Covid-19 epidemic on the development of type 1diabetes. This will be done in two ways: a clinical study and an epidemiological followup. During the next two years, adult patients with newly diagnosed type 1 diabetes willbe asked to participate. Type 1 diabetes will be diagnosed by usual means and a mixedmeal tolerance test will be performed at time of diagnosis and after one year to evaluatebeta-cell function. People with type 1 diabetes and serologically documented previousSARS Covid-19 will be compared with people with no previous infection regarding beta-cellfunction and fate of insulin secretion. In addition, we will estimate the number of newdiagnosed type 1 diabetes patients compared to previous years.

The Coronavirus has caused containment of more than a third of the world's population.Containment can drastically change lifestyle habits, including eating habits such as thenumber of meals, meal times or their composition. However, there is currently no data onthe influence of confinement on eating habits.